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Grounded in excellence and driven by innovation, our Industrial Operations and Product Supply (IOPS) team is responsible for the production of Regeneron products.

IOPS successfully manufactures a range of biopharmaceuticals for patients worldwide, including our approved therapeutic proteins and those involved in clinical studies.

Our operations follow strict adherence to current Good Manufacturing Practices (cGMP) and use cutting-edge analytical equipment, automated laboratory information management systems and electronic document management systems, all of which are supported by an extensive calibration, validation and preventive maintenance program. Our independent clean-room suites with ultra-modern clean utilities support both single-use and stainless steel cell culture bioreactors and large-scale chromatography systems designed to produce and purify our product candidates.

Supported by a highly skilled team of professionals, our integrated teams bring an unsurpassed expertise in developing, operating, optimising, validating and licensing the complex manufacturing processes required for production of biopharmaceuticals.

Take a behind the scenes look at how we produce the highest-quality medicines for patients as efficiently as possible.


Our dedicated Industrial Operations and Product Supply (IOPS) team turns cutting-edge science into innovative biologic medicines to improve the lives of patients worldwide. Our commitment to operational excellence and patient safety ensure we consistently produce the highest quality medicines. Click through the manufacturing process steps below to learn how we turn science into medicine. Download the full process graphic.



In 2019, Industrial Operations and Product Supply (IOPS) Rensselaer was recognized by the Shingo Institute with their highest award, the prestigious Shingo Prize, for operational excellence. Learn how we challenge the status-quo and foster a culture where continuous improvement is not just a metric— it's a mindset for everyone, every day to do better.


IOPS has been manufacturing large-scale biologics since 2003, and has a long-term commitment to manufacturing growth and expanded operations across the globe.

The Rensselaer, NY facility has grown at a rapid pace since its acquisition in 1993. In 2018 Regeneron committed to invest up to $800 million and create 1,500 new full-time jobs in the greater Capital Region by the end of 2024.

Since 2014, Regeneron has invested more than $1 billion to transform a vacant former computer manufacturing factory into the largest bulk biologics production facility in Ireland. Today we are among the areas largest private employers helping drive economic growth in the region.

Explore our Irish operations
The People Beind the Science: Regeneron Scientist, Annie

A little girl sits cross-legged, devouring a series of books about the earth. Captivated, she continues with the history of dinosaurs, one page at a time.

"I distinctly remember looking at descriptions of the earth's core thinking, 'How do you know this??' It was in that moment that I decided I had to know more."

Read Annie's story
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